You can use ManyCam with Loola is two mode:
RTMP mode: by streaming RTMP directly from ManyCam to the Loola servers
RTMP mode enables greater stability, quality and control over the stream parameters, while Webcam mode is more suitable for limited network bandwidth scenarios.
Selecting Desktop Sharing in ManyCam:
Right-click the main video area and select "Desktop":
In Webcam mode, Loola captures the ManyCam virtual camera.
Select both the ManyCam camera and mic in Loola via the source selection:
In case you get "no camera" error, please try the following:
2. Select ManyCam in Loola (see above)
3. Open ManyCam and start streaming!