Yes. There are two ways to use XSplit with Loola: 

  1. Webcam mode
  2. RTMP mode

RTMP Mode:

Set up new custom RTMP:

Set Encoder Parameters and your Loola RTMP Key + URL:

Set the x264/H.264 profile to "main" by entering "&ex:profile:main" in extra encoder parameters:

Also make sure to set keyframe every 2 seconds and Strict CBR mode.

See additional encoder parameters here:
https://www.xsplit.com/blog/how-to-specify-extra-encoder-parameters

Webcam Mode:

In Webcam mode you will use the XSplit built-in Virtual Camera (XSplitBroadcaster).

Note: XSplit only output video to its virtual camera. Capturing audio directly from XSplit requires to setup a Virtual Cable (Windows) or Soundflower (Mac).

Selecting the XSplit virtual camera in Loola is done through the video/audio sources menu:


Setting portrait output resolution:

In order to work with Portrait resolutions, you will need to add those resolutions first in XSplit:


Next, select the newly added resolution:


In Webcam mode, make sure to select the new resolution in Loola:

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